The suitable condition of the Prins reaction was obtained.

得到了该反应的适宜条件。

SOX degenerate primer PRINS revealed more SOX gene loci and proved further that SOX genes were not clustered on human chromosomes.

SOX基因兼并引物延伸发现了更多的SOX基因位座，并进一步证实该家族基因在基因组中是散在存在的。

Methods Chromosomes X, 18 were detected by the primed in situ labeling (PRINS) in eight samples of female peripheral blood cultures.

方法应用原位引物标记(PRINS)在8例女性外周血淋巴细胞培养标本中检测了X、18号染色体。

Purpose To study the feasibility of PRINS for rapid prenatal diagnosis of fetal 18 aneuploidy in metaphase cells from umbilical blood.

目的探讨引物原位标记法（PRINS）结合经腹脐血穿刺，应用于脐血中期细胞快速产前诊断18号染色体数目异常的可行性。

We also set up a more stable method of multicolor PRINS protocol in human cultured lymphocyte metaphase cells, and evaluate its veracity.

随后在人类外周血淋巴细胞中建立了一个稳定的多色prins标记方法并评估其标记效率。

Primed in situ labelling (PRINS) contributes to the elucidation of the organization of eukaryotic chromosomes and provides an alternative way to localize gene on chromosomes.

染色体上引物原位延伸标记在研究染色体结构和基因定位等方面具有重要意义。

CONCLUSION: The technique of rapid PRINS could be used to detect chromosomes in frozen section tissues, and the chromosomal abnormalitie s would be helpful in diagnosis of NPC.

结论：快速引物原位标记技术可用于鼻咽癌冰冻组织切片中染色体的检测，染色体数目的改变可作为鼻咽癌诊断的重要参考指标。