It really goes against the grain to have to work on a Sunday.

星期天还得上班的确不合常情。

Privatization goes against the grain of their principle of opposition to private ownership of industry.

私有化与他们反对产业私有制的原则相违背。

She is girl who likes against the grain.

她是一个顺毛驴（against the grain）的女孩。

It went against the grain to let him win.

让他赢违反了他的意愿。

Why do you always have to go against the grain?

怎么总是个格格不入？

A lie went against the grain, but it was necessary.

撒谎违背我的意愿，但又是必要的。

Underhand work of that sort goes against the grain with me.

做那种偷偷摸摸的勾当不是我的为人。

But what is asked of us here goes against the grain of our human nature.

但是，上主要求我们所做之事有违人性的本质。

Thinking different doesn't just mean intentionally going against the grain, though.

但是，不同凡“想”并不意味着故意违背常规。

Such a retreat into privacy went strongly against the grain of Greek thinking, however.

可是，归隐山林和希腊人的想法有着强烈的冲突。

It goes against the grain for me to accept money merely for giving somebody a helping hand.

仅仅因为帮助了 某人而要接受钱财，那是与我意愿相违的。

He goes against the grain in every way but most noticeably in how he dresses: eccentric and colorful.

他以各种方式反对谷物，但最显着的是如何穿衣服：偏心和丰富多彩。

Some people, however, go against the grain by pursuing a life of "inaction", simplicity and tranquility.

与之相反，有些人却在日益追求着一种生活的“无为”与恬静淡泊。

At the outset, you must realise that success is unlikely if you go wholly against the grain of human nature.

首先，你要明白，任何违背人类自然规律的行为或言论都是不会使你取得成功的。

Here's a little known confidence booster: when you follow your own path, especially when you go against the grain.

以下是一个不出名的自信推进法。当你走自己的路时(即使你跟别人格格不入)，你也会无比的兴奋。

In the end, the people that are able to go against the grain of society are the truly great people in our world.

最后，和社会的期望背道而驰的人才是真正的伟人。

Her brother would rather have a little, and do what he likes, than acquire great deal by working against the grain.

她的弟弟宁可收入少而做他喜欢的事情，不愿为了赚大钱而做与兴趣不合的事。

Investors say this independent streak helps Texans pick stocks to short because they're not afraid to go against the grain.

投资者说正是这种独立性帮助德克·萨斯人挑选卖空股票，因为他们不惧怕反其道而行。

But others do not seek to protect the environment, and standing against the grain, one would suffer losses compared to others.

有时候不是我们不想环保，是其他人都不环保，自己环保了就是吃亏。

All of the problems listed in the previous section derive from trying to go against the grain and treat the UI as a backing store.

前面击节中列出的问题都是应为违背了这个原则并且把UI当作数据存储的地方。

People championing new ideas, especially if they are potentially disruptive new ideas, are going against the grain of what the business is currently doing.

支持新思想(特别是可能引起混乱的新思想)的人会对组织开展业务的现状提出挑战。

Rising wealth is clearly not the same as moral progress, he says. But his most interesting ideas are those that run against the grain of post-crisis soul-searching.

他说，愈来愈多的财富固然不能不能跟道德进步相提并论，但是他最有趣的，则是那些与后危机时代深省所相悖的观点。

It needs to go against the grain and train itself to focus on the value of data and the likelihood it will be compromised, rather than on how a compromise might occur.

IT人员需要不走常规路，对自己进行培训，以便关注数据价值以及数据受到危及的可能性，而不是关注如何可能受到危及。