Histone H3 along with H2A, H2B, and H4 form the eukaryotic nucleosome octamer core.

组蛋白 H3 与 H2A，H2B，H4 共同构成了真核生物核小体的八聚体核心。

Nucleosome is the basic unit of chromatin.

核小体是染色质的基本单位。

Anti-nucleosome antibody; Lupus erythematosus; ELISA.

抗核小体抗体；系统性红斑狼疮；elisa。

Histones that come together to form the core of the nucleosome.

在一起形成核小体核心的组蛋白。

An octa-mer of histones package DNA into a structure called a nucleosome.

一种组蛋白的八聚物把DNA打包成一种叫做核小体的结构。

The general features of nucleosome structure appear to be similar in all eukaryotes.

体结构的一般特性似乎在所有的真核生物中都很相似。

With this technique, total chromatin is first cut into single nucleosome-sized pieces.

用这个技术，总的染色质首先被切成单个核小体大小的片断。

Histone H3 is one of the four histones, along with H2A, H2B, and H4, which form the eukaryotic nucleosome octamer core.

组蛋白H3与其他类型的组蛋白分子H2A， H2B， H4共同构成了真核生物核小体的八聚体核心。

These modifications regulate histone-DNA interactions, adding a new dimension to the epigenetic regulation of nucleosome mobility.

这些修饰调控组蛋白- DNA相互作用，为核小体迁移的表观遗传调控添加了新的维度。

It has been known for some time that the acetylation of N-termini of core histones in nucleosome is associated with gene activation.

人们很早就注意到，真核细胞中核小体核心组蛋白N-端尾部的乙酰化水平与基因活化密切相关。

The nucleosome is therefore a key target of genetic processes in a cell and a focus of scientific investigations into how normal and diseased cells work.

因此核小体是细胞内遗传过程的一个关键靶标，也是解密正常与异常细胞工作方式的科学探索活动的一个焦点。

To adapt to various states of chromatin, corresponding histone variants are incorporated in nucleosome, and certain modifications also occur on the variants tails.

对于不同状态的染色质，核小体中会组装入相应的组蛋白变体，并且各种组蛋白变体的尾部也能发生多种修饰。

To adapt to various states of chromatin, corresponding histone variants are incorporated in nucleosome, and certain modifications also occur on the variants' tails.

对于不同状态的染色质，核小体中会组装入相应的组蛋白变体，并且各种组蛋白变体的尾部也能发生多种修饰。

In eukaryotic cells, the fundamental unit of chromatin is nucleosome, which is composed of a histone octamer with two copies of HA, HB, H and H and base pairs of DNA.

真核细胞中，核小体是染色质的基本单位，它由两个拷贝HA、HB、H 和H所组成的核心组蛋白八聚体，及缠绕于其上的bp DNA构成。

Core processes of epigenetic inheritance include DNA methylation, histone modification, nucleosome remodeling, nuclear dynamics and chromatin interaction with non-coding RNAs.

核心过程的表观遗传的产业包括DNA甲基化、组蛋白改性、核小体重建、核染色质动力学和互动子都存在。