Is there any evidence that there is anything superior to metformin?

那么是否有证据表明有其它药物优于二甲双胍？

Prof Weng: I will say that I believe metformin is still the first-line.

我认为二甲双胍仍然是一线治疗药物。

Prior studies showed a lower cancer risk in diabetics who took metformin.

之前的研究表明服用二甲双胍的糖尿病患者患癌率降低。

Metformin probably indirectly improves insulin sensitivity by reducing glucose.

二甲双胍可以通过降低血糖间接改善胰岛素敏感性。

High dose YSTZT group had similar blood glucose lowering effect as metformin group.

其高剂治疗组的降糖效果与二甲双胍组相似。

The effect of metformin in the treatment of obese females with amenorrhea was observed.

本研究观察二甲双胍对肥胖女性伴停经的治疗效果。

Metformin hydrochloride is an orally administered biguanide widely used in clinical medicine.

盐酸二甲双胍是目前广泛用于临床医学的双胍类降糖药。

The biguanide metformin is believed to lower plasma glucose without affecting insulin secretion.

目前认为双胍类药物二甲双胍降低血糖但不不影响胰岛素分泌。

Objective To investigate the protection of metformin on kidney in non-diabetic hypertension elderly.

目的研究二甲双胍对老年非糖尿病性高血压肾脏的保护作用。

CONCLUSIONS These results suggest that metformin use may be associated with a reduced risk of cancer.

结论：这些结果显示，使用二甲双胍可能降低患癌症的风险。

As a result, sage is sometimes called nature's metformin since it performs like the common antidiabetes drug.

因此鼠尾草有时被称为天然的二甲双胍，这就是因为它表现出了一般降糖药的特性。

Objective To compare the effect of glimepiride and metformin in the treatment of metabolic syndrom (MS).

目的比较格列美脲与二甲双胍对代谢综合征(MS)患者的治疗效果。

In the current study, metformin was shown to be safe, and may be associated with favorable clinical outcomes.

在目前这项研究中，二甲双胍被证明是安全的，同时可能与有益的临床终点相关。

Objective: To observe the efficacy of Diane-35 combined with metformin treat polycystic ovary syndrome (PCOS).

目的：观察达英- 35联合二甲双胍治疗多囊卵巢综合征(PCOS)的疗效。

Pioglitazone was tested in combination with a sulfonylurea, insulin, or metformin in 8 trials (8501 patients).

吡格列酮联用磺脲类、胰岛素或者二甲双胍用于8项试验(8501个病人)。

Every single study has shown that metformin lowers blood sugar and all kinds of other things that are of value.

所有的研究都显示二甲双胍可以降低血糖，改善相关的指标。

It's also possible, however, that metformin is working more directly on the tumor process, the researchers said.

研究人员说，也有可能二甲双胍更直接作用于肿瘤发生过程。

The American Diabetes Association already recommends metformin, which has been proven to lower the risk of heart disease.

美国糖尿病协会已经推荐了二甲双胍，该药已被证明可以降低心脏病的风险。

The need for reevaluation of thyroid function in these patients within 6–12 months after starting metformin is indicated.

这就提示我们对于此类病人在使用二甲双胍的前6-12个月要对其甲功进行复查。

ObjectiveTo investigate the possible mechanism of kidney tissue damage and protective effect of metformin in diabetic mouse.

探讨糖尿病鼠肾脏组织损伤的可能机制及二甲双胍的保护作用。

CONCLUSIONS -monotherapy with GLP-1 and metformin have equal effects on plasma glucose and additive effects upon combination.

结论：GLP - 1和二甲双胍单药治疗对血糖效果相同，联合治疗会产生叠加效果。

Scientists hope that the metformin-chemo combination will result in a need for less chemo, thereby reducing painful side effects.

科学家希望二甲双胍-化疗药物联合用药能够减低化疗药物的剂量，从而减轻化疗药物令人痛苦的副作用。

Objective:To assess the efficacy of cyproterone acetate (CPA) and metformin in the treatment of polycystic ovary syndrome (PCOS).

目的：探讨复方醋酸环丙孕酮（CPA）联用二甲双胍治疗多囊卵巢综合征（PCOS）的临床疗效。

Objective: To assess the therapeutic effects of metformin on insulin resistance and hyperandrogenism of polycystic ovary syndrome.

目的评估二甲胍对多囊卵巢综合征的胰岛素抵抗和高雄激素血症的治疗作用。

One recent study found that metformin may lower a diabetic patient's risk of developing pancreatic cancer by as much as 60 percent.

一个研究结果发现，二甲双胍或许能够降低糖尿病患者患胰腺癌的风险几率达60%。

RESULTS the concentrations were incomplete for enteric-coated Metformin Hydrochloride tablets after the same doses were administrated.

结果在测定方法与给药量相同的情况下，肠溶片的血药浓度数据不完整。

We propose that metformin improves diabetes-associated vascular disease both by lowering blood glucose and by its effect on PTP regulation.

我们认为二甲双胍改善糖尿病相关的血管疾病是通过降糖及调节PTP 效应的双重作用而实现的。

Some common medications include metformin, which is available generically and also known by the Bristol-Myers Squibb brand name Glucophage.

一些常用药包括非专利药二甲双胍，它是百时美施贵宝公司的产品，商品名叫格华止。

Metformin was developed from the French lilac plant, known in the Middle Ages to control excess urination, a symptom of uncontrolled diabetes.

二甲双胍是从法国丁香植物中开发的药物，丁香在中世纪就被用于控制尿频，一种未控制的糖尿病的症状。