The chromatin remodeling and histone acetylation were associated with transcription activation.

真核基因活化与染色质的重建及组蛋白的乙酰化相关.

Epigenetic modification such as histone acetylation plays a key role in occurrence and development of cervical cancer.

组蛋白乙酰化等表观遗传修饰在宫颈癌的发生及发展中具有重要作用。

The level of histone acetylation plays an important role in progression, proliferation and differentiation of leukemia.

组蛋白乙酰化水平的异常在白血病的发展 、 增殖和分化中起着很重要的作用.

HDAC and histone deacetylase inhibitors (HDI) can affect expression of some specific genes and induce cell differentiation growth arrest and apoptosis through regulating histone acetylation level.

组蛋白脱乙酰基酶与组蛋白脱乙酰基酶抑制剂通过对组蛋白乙酰化水平的调控，影响特定基因的表达，改变细胞周期的进程。

The modification for histone acetylation is of great importance for formulation and development of tumors in the epigenetic study of tumors.

在肿瘤的表观遗传学研究中，组蛋白的乙酰化修饰对肿瘤的发生发展起重要作用。