What is my conclusion? I think, there is a significant pain in today’s PDM / PLM market status quo.

我想，今天PDM/PLM市场现状的痛楚是显而易见的。

Whilst four studies showed significant pain relief for the active treatment, three were of poor quality.

虽然有四项研究结果提示治疗组有显著的镇痛效果，但其中三项研究质量较差。

This is causing occasional, but significant pain to developers by forcing them to chase phantom test failures.

这将给开发人员带来虽然是偶尔的，但却是严重的困难，它将迫使他们追赶虚幻的测试失败。

Kobe Bryant continues to play through significant pain whenever his damaged right pinkie is hit during a game.

科比依然在带伤的情况下参加比赛，但是只要他受伤的右手指碰到球，他会觉得很疼。

In addition to keeping a prisoner awake, the simple act of remaining upright can over time cause significant pain.

此外，以保持一名囚犯醒来，简单的行为，剩下的一身正气，可以在一段时间内造成巨大的痛苦。

Practically it's unlikely that this will result in significant pain relief for pain in areas other than the hands and the ongoing duration of the relief is not known.

实际上，这要使双手以外的疼痛得到明显缓解似乎不太可能，并且起效的持续时间尚不清楚。

Practically, it's unlikely that this will result in significant pain relief for pain in areas other than the hands, and the ongoing duration of the relief is not known.

实际上，这要使双手以外的疼痛得到明显缓解似乎不太可能，并且起效的持续时间尚不清楚。

In that study about half the patients in both the real and fake acupuncture groups reported significant pain relief compared to only 27 percent of those receiving traditional back care.

在那次研究中，真针灸组和假针灸组都有近半的比例获得了显著的疼痛缓解，而相比而言这个比例在接受传统背部护理的患者中只有27%。

Indications for the treatment of ingrown toenail include significant pain or infection; deformed, curved nail known as onychogryposis; or chronic, recurrent nail-fold inflammation (paronychia).

治疗嵌甲的适应症包括，显著疼痛或感染；变形，趾甲弯曲（甲弯曲） ；慢性，复发性甲皱炎症（甲沟炎）。

Harpagoside (one type of iridoid) is highly concentrated in devil's claw root and has been reported in some laboratory studies to have significant pain-relieving and anti-inflammatory properties.

哈巴俄苷(一种类型的环烯醚萜)是高度集中在魔鬼的爪根，并已在一些实验室的研究产生重大止痛和抗发炎的特性。

If you can elicit pain at a specific point in a bone, muscle or joint by pressing your finger into it, you may have a significant injury.

如果你把手指压在骨头、肌肉或关节的某个特定部位，就能引起疼痛，那你可能受到了严重的伤害。

The only group with significant symptomatic improvement in pain received proparacaine hydrochloride 0.5%-and only 55% had decreased pain with treatment.

只给痛苦症状显著上升的一组使用了浓度是0.5%的丙美卡因氢氯化物，但使用后，这组也只有55%的人感到疼痛有所缓解。

As such JSF 2.0 is a significant overhaul of the JSF specification and aims to address a number of the key pain points developers encounter when working with the web framework. Key changes include.

JSF 2.0是JSF规范的一次重要革新，其目的在于解决开发者使用Web框架时所遇到的诸多问题。

If you can elicit pain at a specific point in a bone, muscle or joint, by pressing your finger into it, you may have a significant injury.

如果能用手指按在疼痛的部位上，明确指出它位于骨头、肌肉或关节的某一点，那么你可能受到了严重的创伤。

In a study of 8, 499 healthy Brits, those who experienced poor support and nasty spats with their significant other were 34 percent more likely to experience a heart attack or chest pain.

一项涉及8 499名健康的英国人的研究表明：那些极少从亲友处获得支持、常常和亲友有口角的人比普通人患心脏病或胸痛的可能性高34%。

Scientists have raised hope that stem cell therapy could provide significant relief for patients disabled by untreatable chest pain.

科学家们对干细胞疗法能够有力地缓解病人无法治愈的胸痛越来越有希望。

Survivors can experience considerable pain for weeks and often have significant scarring where the tentacles made contact.

幸存者会经受数周的剧痛，而且触手所袭之处，通常会留下醒目的伤疤。

When the volunteers were looking at a picture of their significant other, they reported about 45 percent less pain, compared with when the picture was of a mere acquaintance.

同看认识的人相比，当志愿者看到他们的另一半的照片时，据报道他们的疼痛减轻了45%。

Conclusion. To prevent axial pain, C7 should not be included in cervical laminoplasty, while detachment of the deep extensor muscles does not result in significant axial pain.

结论：鉴于深部肌肉的剥离不会导致明显的轴性疼痛，那么为了防止轴性疼痛，C7就不应被包括在颈椎板成型术中。

The brain responses to each pain state were then rigorously examined and statistically evaluated and compared for significant differences.

同时检测大脑对每种疼痛状态的反应，并用分析得出有统计学意义的差别。

Well there was a programme recently on the BBC about Thomas Pain, and it showed that he actually had a significant affect on the whole world.

BBC上最近有一个节目是关于托马斯·佩因的，说的是他在世界上确实地造成了重大影响。

No significant correlation was found between or among the presence of spasticity, neuropathic pain, and ASIA score at final visit.

在痉挛、神经性疼痛和最终的ASIA评分之间无明显相关性。

Results. No significant difference in the Physical Function, Role Physical, Bodily Pain, and General Health domains was detected between the infection group and control group.

结果：感染组和对照组在生理功能、角色生理状况、躯体疼痛、总体健康方面无显著差异。

Mildly and severely ill patients exhibited significant reduction in visual analog scale overall pain severity at the study endpoint.

在试验终点，轻度和重度患者直观类比量表中的所有痛苦程度都出现明显减小。

There were significant reductions in overall pain in both study groups at each follow-up assessment.

在随访评估时，两个研究组中整体疼痛分数显著降低。