Anxiety disorder; Depressive disorder; Sertraline; Doxepin.

焦虑症；抑郁症；舍曲林；多虑平。

Objective: To improve synthesis of sertraline hydrochloride.

目的：改进盐酸舍曲林的合成工艺。

The invention discloses a method for the racemization of sertraline isomer.

本发明公开了一种外消旋化舍曲林异构体的方法。

Fluoxetine or sertraline can be given during the 14 days before the menstrual period.

氟西丁或舍曲林可以在经前14天开始服用。

OBJECTIVE: To compare the efficacy and side effects of sertraline and clomipramine in treatment of OCD.

目的：比较舍曲林和氯丙咪嗪治疗强迫症的疗效和不良反应。

Objective To appraise the efficacy and side effects of sertraline in treatment of senile depressive disorder.

目的评价舍曲林对老年期抑郁症的疗效和安全性。

Objective: To investigate the compliance and relapse rate of senile depressive patients treated with sertraline.

目的：探讨舍曲林治疗老年抑郁症的长期依从性、复发率。

It may also be produced from sertraline hydrochloride solvate and hydrate forms, and crystallized form new solvent systems.

它还可以由盐酸舍曲林溶剂化物和水合物晶形以及结晶形成新的溶剂系统来制备。

Researchers say the mood boosters sertraline and citalopramare least likely to interact with commonly used cardiac medications.

研究学家说，情绪助推器舍曲林和citalopramare与常用心脏病药相互影响的可能性很小。

Synthesis methods for new drug Sertraline were reviewed and their advantages and disadvantages were described with 33 references.

综述了抗抑郁药舍曲林的各种合成方法，并评价了其优缺点。参考文献33篇。

Sertraline hydrochloride form VII may be produced by suspending sertraline chloride polymorph V in water, followed by filtration.

盐酸舍曲林晶形VII可通过将盐酸舍曲林多晶型物v悬浮在水中继而过滤来制备。

Sertraline hydrochloride Forms V and VI may be produced from either sertraline hydrochloride or sertraline base by crystallization.

盐酸舍曲林晶形v和VI可通过结晶由盐酸舍曲林或舍曲林碱来制备。

Accordnig to the present invention, sertraline hydrochloride Form II may be produced directly for sertraline base or sertraline mandelate.

根据本发明，盐酸舍曲林晶形II可直接由舍曲林碱或扁桃酸舍曲林制备。

The results showed this method would be suitable for determining several residual solvents and quality control of sertraline hydrochloride.

该法能分离多种有机溶剂，可以作为质量检查方法。

It can also be synthesized from the solvent system of sertraline-hydrochloride solvate and hydrate crystal and the crystallization solvate.

它还可以由盐酸舍曲林溶剂化物和水合物晶形以及结晶形成新的溶剂系统来制备。

The patients were receiving mood stabilizers, had moderate to severe depression, and participated in a 10-week trial of sertraline, venlafaxine, or bupropion.

患者当时正在接受心境稳定剂治疗的。 他们有中度到重度的抑郁，同时还参与了10周的舍曲林、文拉法辛或是安非他酮的实验。

If bupropion is found to be more effective for smoking cessation than sertraline, the investigators plan to repeat the trials in non-depressed pregnant women.

如果安非他酮在戒烟上确实比舍曲林更为有效，研究者计划在无抑郁症的孕妇中重复该项试验。

OBJECTIVE To evaluate the effect of cognitive behavior treatment or high pressure oxygen therapy combined with sertraline on anxiety index in chronic insomnia patients.

目的：评价高压氧、认知行为治疗和舍曲林对慢性失眠患者焦虑指数的影响。

Conclusions: using a combination of quetiapine and sertraline to treat depression has a much better effect than merely using sertraline alone, and the former was well tolerated.

结论：奎硫平合并舍曲林治疗抑郁症的疗效优于单纯使用舍曲林，且耐受性好。

Pharmaceutical compositions containing sertraline hydrochloride Forms II, III and V through X, the methods of treatment using such pharmaceutical compositions are also disclosed.

也公开了含有盐酸舍曲林晶形II、III和V - X的药物组合物，和应用上述药物组合物治疗的方法。

Results showed that morepatients in the sertraline plus naltrexone group (53.7 percent) were abstinentfor the 14 weeks of treatment than the patients in the other groups combined.

治疗后抑郁消失的定义是在治疗的最后3周，HAM-D得分不超过9分。 治疗结果显示舍曲林联用纳曲酮组有更多患者（53.7%）经过14周的治疗摆脱酒瘾。

Nor were there significant differences in the risk of suicidal ACTS within the SSRI drug class in the comparisons among citalopram, fluvoxamine, paroxetine, sertraline, and fluoxetine.

同样，这种自杀行为的风险差异也未表现在SSRIs类药物之间：西酞普兰、氟伏沙明、帕罗西汀、舍曲林和氟西汀。