Each requires substantial change in the way we think and function.

每个议题都需要我们在想法和职能上做根本上的改变才能因应。

The only substantial change in the results is that leverage is no longer significant.

独一的本质性的改动，成果是，杠杆率是不再具有很主要的意义。

It takes approximately six weeks to make a substantial change in a pitcher's delivery.

投手的投球要花六周才能做出实质性的改变。

The substantial change in the story came after the White House decided to stop providing details about the firefight.

实质性的变化在白宫决定停止曝光双方交火的细节之后才出现。

But another substantial change is taking place, I think English itself is no longer really viewed as a second language.

而英语正在发生一种实质性的变化：英语本身不再被视为第二语言。

Butt another substantial change is taking place-I think English itself is no longer really viewed as a second language.

而英语正在发生一种实质性的变化化——英语本身不再被视为第二语言。

Also happening at the same time, I can see, is a substantial change in the way readers are receiving the fiction I write.

同时另外一个我能看到的重大的变化就是，读者们接受这些故事的方式上的变化。

If you want to effect substantial change in your life experience, you must think thoughts that feel different as you think them.

如果你想在你的生活经历中发生物质性的改变，当你思考他们时，你必须思考那些感觉不同的思想。

Therefore, though ABC is continually researched, it certainly occur substantial change to the counting model of cost in domestic enterprises.

因此随着我国对作业成本法不断深入的研究，必将对我国企业的成本核算方式产生本质上的改变。

Our approach of reusing existing code, instead of taking on the challenge of direct pixel modification, will require a substantial change to the EffecTV architecture.

我们要重用现有的代码，而不是直接修改像素，这要求对 EffecTV 的体系结构进行一项实质性的修改。

The Borrower shall procure that no substantial change is made to the general nature of the business of the Borrower from that carried on at the date of this Agreement.

借款人应保证借款人从事的业务的一般性质自本协议签订日开始无任何重大变化。

This substantial change has triggered an chain reaction among physics that has spread to classical physics, cryogenics, quantum physics, informatics and cosmology so far.

这个根本性的变化在物理学中触发一个连锁反应，这个反应目前已经波及到了经典物理学，低温物理学，量子物理学，信息学和宇宙学。

As an important principle during the performance of contract, the substantial change of circumstance system is provided in continental law system and common law system countries.

情势变更原则作为合同履行的重要原则，在大陆法系及英美法系国家均有规定。

The substantial change occurred because of the change of the dynasties and the turbulent age, and because of the strong feelings that the poets wanted to express their new aspiration.

这种巨大的转变是朝代更迭的动荡不安造成的，是为表达词人的人生理想而形成的。

It shows no substantial change in global mental health resources since 2001, while there continue to be marked and growing differences in availability between high - and low-income countries.

它显示自2001年以来在全球精神卫生资源方面无重大变化，而高收入国家与低收入国家之间在可获得性方面继续存在显著和日益扩大的差别。

Considering the formation conditions of hard domains, it is reasonable to deduce that the increase of the number of VBLs in their walls leads to substantial change of their static characteristics.

从形成条件可以合理地推论，畴壁中VBL数目的增加导致硬磁畴静态特性的质的变化。

He said substantial money should also be offered to help poor countries adapt to climate change, but ultimately rich nations must make cuts in emissions.

他说，也应该支付大量资金帮助贫穷国家适应气候变化，但是，最终富裕国家必须削减碳排放。

It takes a substantial amount of training and incentives to change behavior in the newspaper sales team.

要改变一个报纸销售团队的行为需要大量的培训和激励。

Enabling teams and individuals to break out of this "infinite loop" and achieve substantial net productivity gains is the change we're making today.

使团队和个人打破这个”无限循环“并实现真实纯粹的生产力的收获是我们今天要做的变化。

They propose that deficiency-love is substantial for as long as our needs are stable, but as we evolve and grow, our needs change.

作者认为：只要我们需求稳定，“匮乏之爱”会很牢固，然而，我们会成长，需求会变化。

The IUCN red list identifies polar bears as a vulnerable species, citing global climate change as a "substantial threat" to their habitat.

世界自然保护联盟红色名录已经将北极熊确定为渐危物种之一，将全球气候变化定义为影响北极熊栖息地改变的“潜在杀手”。

You might be keen to take a sabbatical or make a substantial commitment of time or energy as a volunteer. You might want to change to a new career that you'd love - but that would bring in less money.

你可能想要一个休假或者自愿做出时间上或精力上的重大牺牲。

The study of "Change", unlike the substantial category, emphasizes aspects in defining properties, form and activities.

与实体范畴不同，“变”学主要侧重于属性、状态和活动的方面。

If substantial market coverage is obtained, there would be no need to change the approach.

如果已获得坚实的市场覆盖率，就无须更改了。

All of them have the potential to change the way we work in substantial ways, threatening to make many people and even experts in their fields obsolete.

但所有趋势都有可能完全改变未来的工作方式，还有可能令很多人，甚至某些领域的专家彻底过时。

They will not make a substantial fractional change in the size of a software package unless the package itself is quite small.

它不会对软件包大小带来实质的改变，除非软件包是很小的。

The collapsibility farmland is easy to change, which make the make building appear substantial settlement, fracture and tilt.

湿陷性黄土地基易变形，会使建筑物大幅度沉降、折裂及倾斜。