The best ratio of adding Azone in Gel is 2%.

优选氮酮的最佳加入浓度为2％。

The best one was the plaster containing 2.0% azone.

但以含2.0%氮酮的甘草次酸钠贴剂，其透皮吸收为最好。

Objective To study the percutaneous permeation of menthol and azone for acyclovir gel.

目的研究薄荷醇和氮酮对阿昔洛韦凝胶皮肤渗透性的影响。

This special advantage of azone attract researchers in the field of medicine and veterinarian.

氮酮的这种独特优势成了近年来人医和兽医关注的课题之一。

OBJECTIVE: to study the bacteriostasis of Azone to penicillin resistant staphylococcus aureus.

目的：研究月桂氮芯卓酮对酮对耐药性金黄色葡萄球菌的抑菌作用。

But this action was no longer increased proportionally When the concentration of Azone above 4%.

但浓度大于4%时促进作用不再成比例的增加。

RESULTS Both Azone and Lepaloine at different concentrations have the role of enhancing permeation.

目的探讨氮酮、杜香萜烯两种渗透促进剂对复方骨质增生贴剂透皮渗透的影响。

AIM: To investigate the effects of penetration enhancer 1-menthol and azone on percutaneous absorption of bifonazole in vitro.

目的：研究透皮促进剂氮酮和薄荷醇对外用抗真菌药联苯苄唑体外经皮渗透性影响。

Methods Rats skin in vitro was applied, studying the effect of different concentrations of azone in Cytarabine ointment on drug permeation.

方法采用小鼠离体皮肤作为渗透屏障，研究不同浓度氮酮对阿糖胞苷促渗作用的影响。

OBJECTIVE: To observe the influence of azone in different concentrations on transcutaneous permeation of aminophylline through in vitro rat skin.

目的：观察不同浓度的月桂氮酮对氨茶碱小鼠离体皮肤渗透性的影响。

Objective To investigate the effect of two kinds of permeation enhancers, azone and clove bud oil, on transdermal permeation of Shuxiong cataplasm.

目的探讨氮酮、丁香油两种渗透促进剂对舒胸巴布剂透皮渗透的影响。

CONCLUSION Transfersulin system with azone and 1, 2-propanediol can improve the penetration efficiency on mice skin and eliminate the blood glucose.

结论：1,2 -丙二醇，月桂氮卓芯酮—胰岛素传递体经皮给药系统可进一步提高胰岛素传递体的透皮吸收效率，降低血糖。

Synthesis of azone was carried out from azacycloheptan-2-one and 1-bromododecane using KOH as condensation agent and PEG-400 as phase transfer catalytic agent.

以氮杂环庚—2—酮和1—溴十二烷为原料合成氮酮，用氢氧化钾为反应缩合剂，PEG—400为相转移催化剂。

METHOD:Using simple cell method and snake skin as transdermal barrier, we determined the transdermal amount of oxaprozin in different Azone concentrations liniments.

方法：应用简单小室法，以蛇皮为透皮屏障，使用不同浓度的月桂氮酮，测量丙嗪的透皮吸收量。

Objective To study the effect of different solvent systems on in vitro penetration rate of aciclovir gel enhanced by Azone for optimizing the formulation of aciclovir gel.

目的研究阿昔洛韦凝胶中的不同溶剂系统对主药体外透皮速率及对氮酮促渗作用的影响，为优化阿昔洛韦凝胶处方提供实验依据。

OBJECTIVE: to study the enhancing effects of azone at different concentrations on percutaneous permeation of compound tinidazole gel and to find out the best concentration.

目的：研究不同浓度的氮酮对复方替硝唑凝胶透皮吸收的作用，并筛选出最佳浓度。

Although 2% menthol crystal or 5% eucalyptus oil was effective as a natural penetration enhancer when used alone, the average penetration rate reached only half of that of 8% azone.

天然类促进剂单用时，2%薄荷醇和5%桉叶油促透效果较佳，但平均渗透速率约为8%氮酮的一半。

To study the effects of different concentration of penetration enhancer including propylene glycol, azone and oleic acid on the permeation of shikonin through excised rat abdomen skin.

研究不同浓度的丙二醇、氮酮和油酸对紫草素透过大鼠腹部皮肤的影响。

RESULTS&CONCLUSION:Azone at different concentrations could promote the permeability of3ingredients of compound tinidazole gel, and2%azone had the most obvious permeation-enhancing effect.

结果与结论：不同浓度的氮酮对复方替硝唑凝胶中3组分的渗透性均有促进作用，其中浓度为2 %的氮酮透皮促渗作用最显著。