They have one abnormal gene from that parent and one normal gene from the other parent.

他们具有来自父母一方的一个异常基因和来自父母另一方的一个正常基因。

Some people are born with an abnormal gene passed on by a parent.

遗传性基因异常：有些人出生时即具有来自父母的异常基因。

Immune regulation disorder is associated with the abnormal gene mutation.

异常基因变成癌基因与免疫功能失调有关。

Inherited genetic abnormality: Some people are born with an abnormal gene passed on by a parent.

遗传性基因异常：有些人出生时即具有来自父母的异常基因。

These findings indicate that, in contrast to derivatives of ESCs, abnormal gene expression in some cells differentiated from iPSCs can induce T-cell-dependent immune response in syngeneic recipients.

这些发现说明，相对于胚胎干细胞的后代，从诱导多能干细胞分化来的某些细胞中异常的基因表达会在同基因的受体身上引起T细胞依赖的免疫反应。

Whether you inherited an abnormal breast cancer gene or acquired it, if you have one normal gene, that gene will still work to control cell growth and prevent cancer.

无论你具有遗传性还是获得性异常乳癌基因，如果你有一个正常基因，这个基因都仍将运行以控制细胞生长并预防基因。

This potassium ion channel gene is the second such gene found by the group to cause abnormal electrical activity leading to death in epilepsy.

钾离子通道基因是该团队发现的第二个引起不正常电活动，从而导致癫痫死亡的基因。

In humans, mutation of the gene for Kv1.1 has been associated with spontaneous seizures, abnormal muscle movements, and motor coordination problems.

在人体中，Kv 1.1对应的基因突变与自发性疾病发作，异常肌肉运作，和肌肉协调问题有关。

09052810 Scientists believe they may have identified a gene that controls abnormal production of sugar in the liver, a very troublesome problem for people with diabetes.

糖尿病人最麻烦的一个问题，就是肝脏合成血糖的功能出现异常。科学家认为他们已经找到了负责控制肝脏这一功能的基因。

No matter how much thinking you do in advance, you may feel overwhelmed if testing shows that you have an abnormal breast cancer gene.

如果测试显示你有异常的乳腺癌基因，不论之前有多少思想准备，你都会深受打击。

My mother has breast cancer and I have the abnormal BRCA1 gene.

我母亲是乳腺癌患者，我的BRCA1基因也不正常。

Conclusion Abnormal methylation of TPEF gene is a frequent event and may become a promising diagnostic marker for early detecting colorectal carcinoma.

结论大肠癌患者TPEF基因甲基化为一频繁发生事件，可望成为大肠癌早期诊断的一个标志物。

Scientists have identified the gene that causes abnormal growth.

科学家已确定了造成畸形发音的基因。

Objective To investigate the role of gene chip technique in screening normal or abnormal developing embryo related genes.

目的了解基因芯片技术在筛查正常或异常胚胎发育的相关基因表达变化中的应用价值。

Conclusion: gene have different degree loses in abnormal chromosome karyogram, result in chromosomal gene linkage not equilibrium and and emergence clinical effect.

结论在染色体异常核型中，均有不同程度的基因缺失，造成基因连锁的不平衡，因而出现一些临床效应。

It is demonstrated that the cancer cells originated from intestinal crypt stem cells, which are responsible for gene mutation, abnormal tissue proliferation and then cancer formation.

有研究表明，大肠癌起源于大肠隐窝干细胞，其基因突变和异常增殖导致大肠癌发生。

There exist hypermethylation, abnormal transcription of FHIT gene and down-regulation expression of FHIT protein in liver cancer.

肝癌中存在FHIT基因高甲基化、转录异常、FHIT蛋白表达下降。

RESULTS: the inhibition rates of majority antitumor drugs in the P53 gene normal group were significantly higher than in the P53 gene abnormal group.

结果：统计比较抗癌药在P 53基因正常组和P 53基因异常组中的抑制率，发现多数抗癌药抑制率前者显著地大于后者。

It has not been confirmed whether GC-resistance is the result of abnormal function of GCR induced by the alteration of GCR gene in children with primary nephrotic syndrome (PNS).

是否是由于GCR基因发生改变引起GCR功能异常，导致PNS患儿对糖皮质激素(GC)耐药，目前尚未见报道。

The mutation or abnormal expression of CHD gene is thought to be related to some human diseases.

CHD基因突变或表达异常与人类某些疾病有关。

The majority of BTCC in this group showed abnormal expression of multiple items of products of gene protein.

本组BTCC大多数表现为多项基因蛋白产物表达异常。

Other 3 young family members with VMD2 gene mutation only had abnormal electrooculogram manifestations.

另外有3个年轻成员虽然携带VMD2基因突变，临床上仅表现为眼电图的异常。

Cancer cells have abnormal levels of methylation, which turns the gene switch off halting the assembly line of critical proteins found in normal cells.

癌细胞甲基化水平的异常导致基因开关关闭，使得正常细胞关键蛋白的装配线出现缺陷。

Often, they want to know if they have an abnormal breast cancer gene because they or a family member has cancer.

通常，她们想知道因为她们或她们的家族成员患有癌症，是否她们也有不正常的乳腺癌基因。

Targeted disruption of the murine Nkx2.5 gene results in abnormal heart morphogenesis, severe growth retardation, and embryonic lethality around E9.5 (1, 2).

靶向缺失小鼠nkx2.5基因会导致心脏形态异常，严重的发育迟缓以及E9.5胚胎致死(1,2)。

Luo et al have proposed that the cause of abnormal development in haploid embryos is that there is a diploid-dependent regulatory apparatus which modulates gene expression.

据罗琛研究发现单倍体胚胎发育不正常是因为单倍体不能选择二倍体依赖的调控系统。

Objective To detect the relationship between the Fas gene mutation of thymocytes and abnormal hyperplastic thymus of patients with myasthenia gravis(MG).

目的探讨重症肌无力（MG）胸腺细胞异常增生的原因，揭示其发生机制。

The mutation of androgen receptor gene, abnormal phosphorylation and abnormal regulation of co-activators contribute to the formation of androgen-independent prostate cancer.

雄激素受体基因突变、多种途径引起的异常磷酸化激活和共激活物的调节失控等是激素非依赖性前列腺癌形成的主要促成因素。

Faulty epigenetic reprogramming in cloned embryo leads to irregularities in gene expression that might result in the abnormal phenotypes in cloning.

异常的表观重编程可以导致异常的基因表达，从而引起克隆动物的诸多异常表型。