STR作为遗传多态性较高的标记，被广泛地运用于群体遗传学的研究。

As high polymorphism markers, STR loci have been widely used in studying population genetics.

方法选择鲁中南地区先天性心脏病患者444例，采用血型群体遗传学及血型血清学方法，进行ABO血型表现型及基因频率分布调查统计。

Methods ABO phenotype and its genetic distribution were investigated in 444 patients with congenital heart disease in center of south region of shandong via blood type genetics and serology.

群体遗传学分析结果表明,取样种群由于杂合子不足造成种群偏离哈迪-温伯格平衡.

The analysis results by GENEPOP software showed that the hypothesis of Hardy Weinberg equilibrium was rejected.